Ebola becoming harder to treat —US experts: rapid mutation could “render treatment and vaccines ineffective”

Ebola mutations
August 2014 AFRICA As countries across the world battle to contain the spreads of the Ebola Virus Disease (EVD), the killer ailment appears to be devising means of circumventing efforts to stop it, researchers have said. Experts claim that the virus is “rapidly and continually mutating, making it harder to diagnose and treat.” This is just as former President Olusegun Obasanjo declared, on Saturday, that the index case, Patrick Sawyer, in a “devilish” connivance with some Liberian authorities, intentionally brought the disease to Nigeria. He also noted that the disease, which he said had become a global problem, had been taking a toll on Nigeria’s economy, charging the Federal Government to partner the World Health Organization (WHO), European Union (EU) and government of America in containing the virus. Sunday Tribune’s finding showed that result of a research by a team of American scientists indicates that the initial patients diagnosed with the virus in Sierra Leone revealed almost 400 genetic modifications, concluding that this could render current treatment ineffective and put vaccines that are being worked on for its cure in danger. According to reports, the team of researchers, under the Broad Institute in Massachusetts and Harvard University, analyzed more than 99 Ebola virus genomes which were collected from 78 patients diagnosed with the disease in Sierra Leona in the first 24 days of the current outbreak. Dr Pardis Sabeti, a senior associate member at the Broad Institute and an associate professor at Harvard University, who was among leaders of the research, said “by making the data immediately available to the community, we hope to accelerate response efforts.
“Upon releasing our first batch of Ebola sequences in June, some of the world’s leading epidemic specialists contacted us, and many of them are now also actively working on the data. We were honored and encouraged. A spirit of international and multidisciplinary collaboration is needed to quickly shed light on the ongoing outbreak.” According to Daily Mail, the researchers’ findings, “reported in the journal, Science, could have important implications for rapid field diagnostic tests. “The team found more than 300 genetic changes that make the 2014 Ebola virus genomes distinct from the viral genomes tied to previous Ebola outbreaks. “They also found variations in the genome sequence indicating that, from the samples analyzed, the outbreak started from a single introduction into humans, subsequently spreading from person to person over many months. “To accelerate response efforts, the research team released the full-length sequences on the National Center for Biotechnology Information (NCBI)’s DNA sequence database, in advance of publication. This means the data is available to the global scientific community.”
He advised Nigerians to brace up by tackling the economic effects of the disease in the country’ urging them to be aggressive with precautionary measures against the disease, since there was no cure yet. Obasanjo said that some Liberian authorities knew of the contagious and deadly illness in Sawyer and allowed him to visit Nigeria. “Ebola is taking economic toll. How do we handle people that are economically affected; not those that are dead or ill? The economic effect has started. How do we reduce, recoup the economic cost of Ebola on communities, nations and the West African region? “When HIV came, they said don’t talk about it. Now, it is Ebola and Ebola is even talking about HIV. We should be doing whatever we can and that is being aggressive in taking precautionary measures to prevent it. “So, it is devilish enough that Patrick Sawyer, in connivance with some authorities from his country, allowed the visit because they know he had it; and he came to Nigeria,” he said. He also called on the world’s pharmaceutical giants to intensify research efforts towards providing either vaccine or curative drugs for the virus. –Tribune
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14 Responses to Ebola becoming harder to treat —US experts: rapid mutation could “render treatment and vaccines ineffective”

  1. niebo says:

    So. . . is President Olusegun Obasanjo suggesting/hinting/declaring that the outbreak of this super-mutating Ebola is somehow a conspiracy? That’s crazy. Or, is it?


    Either way, here’s a link that illustrates/explains how viruses mutate:



  2. Shepherd says:

    EBOLA confirmed in 6 nations
    Guinea, Sierra Leone, Liberia, Nigeria, Senegal and Congo
    Ebola patients sent for treatment to Spain, London England, USA


  3. Joseph Sonny Skies says:

    I am glad that some are recognizing and talking about the economic disaster this pandemic can cause. It will be devastating in the USA as well because health insurance in this country is nearly non existent and HSA and overpriced Obama care plans are a farce. Plus the amount of homeless people in all of our cities are more staggering than many can imagine allowing for diseases to spread extremely rapidly. So many people will not be able to pay for the treatments to disease that the payments for disease treatment will suck the money right out of the rest of the economy and even the health care providers will not get enough reimbursements to stay solvent and will have to choose between not offering care for those who cannot pay [ riots in the streets ] or accepting financial losses. The government will print more monopoly money but all that will do is make a loaf of bread cost a day’s wages as the Bible suggests.


  4. Geraldo says:

    Tekmira stock went up more than 70 points in one week a while ago. CNBC announced it! They along with GSK are rushing to provide vaccines for all!


  5. Nurse Rachette says:

    This news should not come as a surprise. Ebola or EVD are RNA based viruses, as opposed to DNA. Which means that it recombines with each infection. It is adapting and evolving for its insured survival.


  6. Why don’t you allow any sharing on Facebook ?


  7. Scott says:

    What are the preventative measures we can take against infection from this current outbreak of Ebola?


  8. as above... says:

    Vaccines are being touted as a “cure” now?


  9. A. Zu says:

    The cure and protection are PRAYERS! Psalms, chapter 91 “You who dwell in the shelter of the Most High, who abide in the shade of the Almighty, Say to the LORD, “My refuge and fortress,my God in whom I trust.”He will rescue you from the fowler’s snare,from the destroying plague….


  10. feedscrn says:

    Three things….

    Earlier in August, the officials were saying that Ebola is a very slow mutating disease. Then they found that the longer it stays in human hosts, the more it mutates.

    The Dem Rep of Congo Ebola is a new strain. It’s still popping up as a novice virus… albiet seemingly unrecognizable as Ebola at times.

    A new vaccination may only cover one type of Ebola at a time. We’ll see.


  11. Labetter@aol.com says:

    I found this comment from a woman on Ebola: “The people who have been studying Ebola are M.D.s not laboratory technicians. they are not research specialists. it is obvious that they have missed the fact that Ebola is coming from conditions that are prone to have serious fungal infections and conditions that can cause a variety of invasive conditions from sporulation inspiration, to consumption, etc.

    When you look at the EM photographs of Ebola it shows distinct fungal growth invasion of tissues.
    I do not believe anyone has ever plated these out for fungus or fungal infections because it looks distinctly like fungus.

    Fungus has many forms that are very deadly. The most important thing is to place victims in negative air pressure conditions and rooms. To not enter the rooms without total biohazard and respiratory protection with something this invasive and deadly.

    Common aspects of fungal invasion are high fevers, brain infections, blood invasion etc.
    It is common in very arid regions of the world for very deadly fungus to exist and be inhaled such as in desert conditions.

    Most people do not have resistance to most fungus types. Most curatives are almost as deadly as the fungus itself.

    The Chinese medical system has found a large number of natural alternative curatives that have shown to be very effective against fungal invasions and are less damaging to the human who has contracted it.

    Feeces are very infective and should be treated as biohazards as they are filled with spores from fungus.

    A case where a person became infected handing feeces of an Ebola victim was treated with immunoglobulins which have been shown to help fight fungal infections.

    M.D’s are not researchers they are physicians. This has been assumed to be a virus because it does not respond to antibiotics. The treatment was done in the field where laboratory analysis was not available. Obviously no plating for fungus was done by a rare and difficult to find Mycobiologist”

    What do you think? She could be right . I was watching Anderson Cooper on CNN and he was interviewing the girlfriennd of the man in Texas with Ebola. She said he became much sicker along with diareah after they sent him home with antibiotics.. My daughter had fungal pnemonia not bacterial pnemonia and she had the same response as antibiotics are MYCOTOXINS and will fuel the demiise of the patent. Any observations or thoughts?


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