Scientists uncover deadly new virus in Africa

September 30, 2012DISEASE - A piece of genetic detective work by an international team has uncovered a deadly virus not seen before that likely caused a small isolated outbreak of acute hemorrhagic fever in central Africa in the summer of 2009. The outbreak, in the Democratic Republic of Congo (DRC), killed two people and left one person seriously ill. The researchers have given the deadly pathogen the name Bas-Congo virus (BASV), after the province where the three people lived. They report their work in the 27 September issue of the online open access journal PLoS Pathogens. The 2009 outbreak of acute hemorrhagic fever started when a 15-year-old boy from a village called Mangala in the DCR suddenly got ill and started bleeding from the nose and gums and vomiting blood. He got worse very quickly and died three days later. A week later, a 13-year-old girl who went to the same school as the boy, started with the same symptoms, which also worsened rapidly, and she also died within three days. Then, again, another week after the girl died, a male nurse who had cared for her started with the same symptoms. He was transferred to hospital and survived. The UCSF team leader was Charles Chiu, assistant professor of laboratory medicine at UCSF and director of the university’s Abbott Viral Diagnostics and Discovery Center. He says in a press release: “These are the only three cases known to have occurred, although there could be additional outbreaks from this virus in the future.” Initial tests for known viruses on blood samples taken from the survivor revealed nothing; however, further genetic tests uncovered a completely new virus. Chiu says the new virus, BASV, is quite unlike other viruses in Africa known to be behind deadly outbreaks of acute hemorrhagic fever, such as Ebola virus, Lassa virus, and Crimean-Congo Hemorrhagic Fever virus. Genetically, BASV bears more resemblance to rabies viruses, which cause a different type of infection, a neurological illness that can take months to develop but invariably kills, explains Chiu. The virus belongs, like rabies, to a family called the rhabdoviruses. “BASV was present in the blood of the lone survivor at a concentration of over a million copies per milliliter. The genome of BASV, assembled from over 140 million sequence reads, reveals that it is very different from any other rhabdovirus,” write the authors. No other rhabdovirus is known to cause the acute, rapid and deadly hemorrhagic fever seen in the three cases in the Congo. For example, rabies can be deadly if untreated, but it doesn’t progress in the rapid and deadly fashion seen with BASV. –Medical News Today
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3 Responses to Scientists uncover deadly new virus in Africa

  1. Elmarie Raaths says:

    Unbelievable

  2. katnea says:

    Question for moderators: I had posted my response (Sept. 30th) regarding “Scientists uncover deadly new virus in Africa” but its now Oct. 7th and I continue to see: “Your comment is “awaiting” moderation.” <— Does this mean that my response has been rejected or what? If my post has been rejected…. I rather see a more clear message like:
    "Thanks for posting, but your response will be held back at this time."
    The reason I ask this question is because…. sometimes my PC has "issues" when it comes to posting via "Wordpress". I usually have better luck when I post here by using "Facebook" but I don't always like to post via that route. However, if I had posted something you feel is inappropriate…I'm sooo sorry as that was never my intention. I enjoy and depend upon this website to bring me all the important fact gathering information that you share here! Anyway…..
    Thank-You, and have a calm and blessed day ♥
    Katnea = )

  3. It simply means, I’ve been too busy to ge to the comments Katnea…

    Wishing you the same,
    Alvin

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