Recovery from a COVID-19 infection could be long, tortuous road for many

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Coronavirus patients declared recovered who later test positive for the disease are still expelling dead lung cells rather than getting a new infection, the World Health Organization (WHO) told AFP on Wednesday.  South Korean health officials reported more than 100 such cases in April, raising concerns that patients who had recovered could become reinfected.  “We are aware that some patients test positive after they clinically recover,” a WHO spokesperson told AFP, without making specific reference to the South Korean cases. “From what we currently know – and this is based on very recent data – it seems they these patients are expelling left over materials from their lungs, as part of the recovery phase.”

People infected with the new coronavirus build up antibodies starting a week or so after infection or the onset of symptoms, research has shown. But it is still not clear, experts say, whether the body systematically builds up enough immunity to ward off a new attack by the virus or, if it does, how long such immunity lasts. As for the recovered patients who tested negative and then, weeks later, positive, more research is needed, according to the WHO. “We need systematic collection of samples from recovered patients to better understand how long they shed live virus,” the spokesperson said.

“We also need to understand if this means they can pass the virus to other people – having live virus does not necessarily mean it can be passed to another person.” In a recent interview with BBC, infectious disease epidemiologist Maria Van Kerhove, part of the WHO’s Health Emergencies Program, explained the “dead cell” scenario. “As the lungs heal, there are parts of the lung that are dead cells that are coming up. These are fragments of the lungs that are actually testing positive,” she said. “It is not infectious virus, it’s not reactivation. It is actually part of the healing process.” “Does that mean they have immunity? Does that mean they have a strong protection against reinfection? We don’t know the answer to that yet.” For some viruses, such as the measles, those who contract it are immune for life. For other coronaviruses such as SARS, immunity lasted from a few months to a couple of years. The pandemic has now killed more than 257,000 people globally and officially infected nearly 3.7 million, although with only the most serious cases being tested the number is believed to be far higher.  –Science Alert

Viral shedding after 30 days? Coronavirus has been found in human feces, more than a month after the patient tested negative for COVID-19. Scientists from the University of Stirling have warned that the findings indicate that coronavirus could spread via sewage. Professor Richard Quilliam, who led the study, said: “We know that COVID-19 is spread through droplets from coughs and sneezes, or via objects or materials that carry infection. “However, it has recently been confirmed that the virus can also be found in human feces – up to 33 days after the patient has tested negative for the respiratory symptoms of COVID-19. “It is not yet known whether the virus can be transmitted via the fecal-oral route, however, we know that viral shedding from the digestive system can last longer than shedding from the respiratory tract.  –Mirror

Sexual transmissibility? Coronavirus was found in semen of recovering and acute male COVID-19 patients in a small study conducted in January and February in China, though it remains unknown, according to the CDC, whether the disease can be transmitted sexually. In the study, originally published on JAMA Network Open and conducted in Shangqiu, China, six patients—15.8%—of 38 COVID-19-positive males had the virus in their semen. “We are learning about this virus on a daily basis…People should be practicing abstinence or safe sex after being sick,” Dr. Anne Rimoin, a professor of epidemiology who focuses on infectious disease spread at UCLA’s Geffen School of Medicine, advised in a CNN interview on the subject.  –Forbes

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